Breaking bonds: Double-helix unzipping reveals DNA physics

Reconstructing accurately how the parts of a complex molecular are held together knowing only how the molecule distorts and breaks up. This was the challenge taken on by a research team led by SISSA's Cristian Micheletti and recently published on Physical Review Letters. In particular, the scientists studied how a DNA double helix unzips when translocated at high velocity through a nanopore, reconstructing fundamental DNA thermodynamic properties from the sole speed of the process.

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Maristella Lunardon (mlunardo)
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mlunardo@sissa.it