SISSA -- PhD in Structural and Functional Genomics
Course Announcement,  Spring 2007
 

Introduction to Bioinformatics and Systems Biology


Lecturer:  Claudio Altafini 
  altafini@sissa.it
  ~altafini

Format

6 lectures

Schedule

February 7th -- February 16, all in Congress Room, Building T, Area Science Park, Bassovizza

Tentative Course Outline



Analysis of Microarray data
  1. low level analysis
  2. high level analysis (model-free)
    • identify differentially expressed genes
    • clustering
    • principal component analysis
    • ontological enrichment
Inferring Regulatory Networks
  1. Bayesian netwroks
  2. Association networks
  3. linear ODE methods
ODEs Models in Systems Biology
  1. Biological processes as ODEs
  2. Elementary modules from reaction kinetics
  3. Qualitative behavior: steady state, stability and multistability
  4. Feedback regulation: examples
     

Slides of the lectures

  • 1st lecture (pdf file)
  • 2nd lecture (pdf file)
  • 3rd-4th lectures (pdf file)
  • 5th-6th lectures (pdf file)