The key of the extraordinary functionality of ribonucleic acid, better known as RNA, is a highly flexible and dynamic structure. Yet, the experimental characterisation of its different configurations is rather complex. A study conducted by SISSA and published in Nucleic Acids Research combines experimental data and molecular dynamics simulations to reconstruct the different dominant and minority structures of a single RNA fragment, providing an innovative method to study highly dynamic molecular systems.
A new approach to reveal the multiple structures of RNA
22 January 2020
Combining experimental data and computer simulations to investigate dynamic molecular systems