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Spliceosome: how the right information is propagated in cells

01 June 2020

A new study of the ‘Istituto Officina dei Materiali’ (IOM) of the Italian National Research Council (CNR) and Sissa (Scuola Internazionale Superriore di Studi Avanzati) sheds light on how the spliceosome works. It is a complex cellular system, composed of proteins and RNA, responsible for a “cutting and sewing” process with which protein synthesis is carried out. Defects in its functioning are involved in more than 200 diseases. The study has recently been published in the Journal of the American Chemical Society, which also dedicated the cover to it.