Dynamical Models in Biology

SISSA -- PhD Course Announcement, Spring 2008

Dynamical Models in Biology

Lecturer: Claudio Altafini

altafini@sissa.it

~altafini

Format

approx. 8-10 lectures

First class: Thursday 14th february, at 14:00, room B
then
- Tuesdays (19, 26 february, 4, 11, 18 march) at 14:00 room A
- Thursdays (21, 28 february, 6, 13, 20 march) at 14:00, room B

Single and two-species dynamics
- qualitative analysis
- predator-prey
- oscillations
Epidemic models
- HIV dynamics
- immunoresponse
- drug action
Precision and adaptation
- Kinetic proofreading
- Bacterial chemotaxis
Whole network dynamical theories:
- Stoichiometric network analysis
- Metabolic control analysis
- Chemical reaction network theory

standard textbooks like
- L. Edelstein-Keshet. "Mathematical Models in Biology", SIAM Classics, 2005.
- J. D. Murray, "Mathematical Biology, Springer-Verlag, 3rd ed. 2001
- E. Sontag, "Lecture Notes in Mathematical Biology", available at the URL: http://www.math.rutgers.edu/~sontag/613.html
M.A. Nowak and R. M. May, "Virus Dynamics", Oxford Univ. Press, 2000.
U. Alon, "An Introduction to Systems Biology", CRC press, 2007.
various sources:
- B. O. Palsson, "Systems Biology", Cambridge Univ. Press, 2006.
- E. Klipp, R. Herwig, A. Kowald, C. Wierling, H. Lerhach, "Systems Biology in Practice", Wiley, 2005.
- M. Feinberg, "Lectures on Chemical Reaction Networks", 1979, available at http://www.che.eng.ohio-state.edu/~FEINBERG/LecturesOnReactionNetworks/