Single Molecule in Biology

International workshop
June 23 - 24, 2015
SISSA

The meeting will focus on ongoing state-of-the-art efforts on developing new ways of detecting interactions between biomolecules at the single molecule level.


Confirmed Plenary Lecture:

CARLOS BUSTAMANTE, University of California at BERKELEY, USA


Invited Speakers:

Miklos Kellermayer - Semmelweis University (Budapest, Hungary)

Ciro Cecconi - Università degli Studi di Modena e Reggio Emila (Modena, Italy)

Marco Capitanio - LENS-Università degli Studi di Firenze (Firenze, Italy)

Motomasa Tanaka - RIKEN Brain Science Institute (Wako City, Japan)

Gijs Wuite - VU University (Amsterdam, The Netherlands)

Ricardo Garcia - Instituto de Ciencia de Materiales de Madrid (Madrid, Spain)

Claudio Rivetti - Università degli Studi di Parma (Parma, Italy)

Francesca Cella Zanacchi - Italian Institute of Technology (Genova, Italy)

Alf Honigmann - Max-Planck-Institute for Biophysical Chemistry (Gottingen, Germany)


Giuseppe Legname, CHAIR
Dan Cojoc and Bruno Samori, Co-CHAIRS


PROGRAM - JUNE 23, 2015

15:00 - Registration

16:00 - Welcome address

16:30-17:30 - Carlos BUSTAMANTE "A Journey Through Cellular Processes: One Molecule at a Time"

18:00-20:00 – Reception


PROGRAM - JUNE 24, 2015

Chair: Bruno Samorì

08:30-09:10 - Miklos KELLERMAYER "Single-molecule biology of the muscle cytoskeleton"

09:10-09:50 - Ricardo GARCIA "Advanced force microscopy and spectroscopy methods for single molecule processes in biology"

09:50-10:30 - Claudio RIVETTI "ppGpp and DksA modulate Escherichia coli RNA polymerase-promoter complex stability and DNA wrapping: a single-molecule study"

10:30-11:00 - COFFEE BREAK

Chair: Giuseppe Legname

11:00-11:40 - Motomasa TANAKA "Latent structural variation in a yeast prion monomer determines strain phenotypes"

11:40-12:20 - Andrea RASPADORI "Conformational equilibria of the prion protein characterized by single-molecule force spectroscopy"

12:20-14:00 LUNCH BREAK

Chair: Dan Cojoc

14:00-14:40 - Marco CAPITANIO "Detection of sub-millisecond biomolecular interactions and protein conformational changes under constant tension"

14:40-15:20 - Alf HONIGMANN "Revealing membrane organization with optical nanoscopy"

15:20-16:00 - Francesca CELLA - ZANACCHI "Light sheet based super resolution imaging of thick samples"

16:00-16:30 - COFFEE BREAK

Chair: Giuseppe Legname

16:30-17:10 - Ciro CECCONI "Direct Observation of Calcium-dependent Misfolding in Single Neuronal Calcium Sensor-1 Molecules"

17:10-17:50 - Gijs WUITE "Acoustic Force Spectroscopy (AFS)"

17:50-18:00 - Closing Remarks


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